So the new canon fodder multiplayer map lore seems to confirm the Created still exist in some capacity during Halo Infinite.
There is described as being a “lingering” Created threat and the Spartan training facility remains concerned with “Fledgling” Created cells. They also use term “Created Affiliates” which is an oddly vague description.
Well I am going make some wild speculation on the use of a few words. 
Given that the UNSC are worried about more AI joining the Created it probably means that the events Cortana set in motion. The idea, or the movement, isn’t really going to entirely go away. Even if the Founder and most powerful of the Created is not there; what she set in motion won’t end.
We also see the term lingering. Now there’s no question, losing Cortana and probably the Guardians would be a near fatal blow. It suggests that some Created threat remains but it’s been vastly reduced in scope. Alternatively it could just be referring to hunters seeking out humans. They avoid saying “remaining” Created. But I’d say it’s still leaning into them not being all that anymore.
I am quite curious by the term “Created Affiliate”. I’d guess that means Prometheans? Bit odd to be vague about Prometheans still being a thing. They’re the only faction we know of fighting with Created. Some Covenant species were going along with Cortanas plan such as the Grunts. Atriox and Esharum describe her as a False God several times. So perhaps some Covenant and maybe some of those human cultists from Hunt the Truth are helping the Created? It’s also possible that the Created might have been able to build their own drones using UNSC factories but then that’s less an affiliate than them physically fighting at that point.
I could see them becoming similar to the Insurectionists. They exist in the lore but aren’t really in the games.