For a first test flight I will say I am lucky to have a second gpu sitting around or otherwise I don’t think I could have gotten the game running at all.
I saw people with the 980 Ti say it wouldn’t load either. GM107-108 cards are not compatible. So GM200 and up are all good. I am sure that the data collected during the flight will correct any loading mistakes for people with a Quadro M6000 or a Tesla card (I don’t neeed it).
For reference (and also good knowledge to be found here):